Low Metabolism and Insulin Resistance Connection

This topic is very important because obesity and type 2 diabetes is an epidemic in the United States and also some other countries all over the world. Dietary fructose consumption is one of the things that is also way higher than it was some time ago. Also, further problems with glucose metabolism lead to other metabolic problems like metabolic dyslipidemia.

Metabolism problems have a close connection to insulin resistance. Furthermore, “Fructose-induced insulin resistant states are commonly characterized by profound metabolic dyslipidemia, which appears to result from hepatic and intestinal overproduction of atherogenic lipoprotein particles.”[1] Further studies have proved a very negative impact of fructose. More people need to understand its negative impact on drinking and eat foods with high fructose additives although they might taste very good.

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The negative effect of high saturated fat diets:

• Weight gain
• Insulin resistance
• Hyperlipidemia
• hypertension

Fructose-induced insulin resistance and other aspects are not good for the overall health. There is no doubt that fructose causes diabetes from studies[2] similar to other diseases.

How to tackle metabolic syndrome?

Nutritional factors play a very big role in this fight. The focus should be preventative nutrition and the control of weight. High-calorie foods that have become highly available is a big no. And only cutting down fat consumption won’t help that much because even studies showed that there are no significant benefits for obesity (you can read more about obesity and metabolism here). The answer is carbohydrates that we discussed in the previous article. Especially I mean consumption of such foods that are high in fructose.

Fructose-rich products to avoid:

• corn syrup
• soft drinks
• juice beverages
• pre-packed foods (breakfast cereals, baked goods)
• sweeteners (e.g., corn syrup sweeteners)

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Fructose metabolism

The human liver is the main organ responsible for metabolizing fructose. But the liver cannot survive dal with such a large amount of fructose (e.g., 85-100 grams per day). It contributes to reduced sensitivity and insulin-glucose intolerance. The major consequences of the high influx of fructose are that “perturbations in glucose metabolism and glucose uptake pathways and a significantly enhanced rate of de novo lipogenesis and TG synthesis.”¹ Fructose insulin response is insulin resistance. Characteristics are metabolic dyslipidemia because of excessive production of atherogenic lipoprotein. Western diets are usually rich in fructose, cholesterol, and fat. People need to know more about glucose vs. fructose metabolism as well as other risks of high fructose consumption. Right supplementation like Balance Cellular MICA-1 can help to gain the right amount of nutrients and other necessary ingredients together with healthy eating choices.

Reference:

[1][1] Fructose, insulin resistance, and metabolic dyslipidemia. Accessed from: https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-5rel=”nofollow”

[2] Gross LS, Li L, Ford ES, Liu S: Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr. 2004, 79: 774-779.

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