Blood Glucose Effects on Inflammation and Weight Gain

Inflammation is a negative process in anybody that in many cases is one of the symptoms of further problems. Many people with additional weight and diabetes also have experienced this problem. That is one of the reasons why it is important to look at inflammation and its connection with blood glucose.

More recent studies show that “nearly 60% of the population has a genetic predisposition for developing diabetes.”[1] There are numerous factors that can lead to insulin resistance, diabetic co-morbidities, carbohydrate intolerance and others. This time we can look at the ones suggested by Dr. Robin Walsh, ND.

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Food addiction by simple carbohydrates

World Health Organization guidelines recommendation is only 5% (about 60 tbsp. of sugar for women) of total energy intake for adults with normal Body Mass Index (BMI). For most of Americans and other people it is way more, and thus there are different health consequences. One of them is that it leads to glucose toxicity. Now about 60% of the population has an inclination for the development of diabetes and/or obesity (BMI is 25 kg/m2 or more).

What leads to glucose toxicity and inflammation?

Dr. Walsh also argues that it takes only 3-6 pounds of extra weight to trigger insulin resistance. It is possible to use medical nutrition therapy to prevent glucose intolerance and other health problems that lead to diabetes.

Inflammation and glucose

Inflammation itself begins in the fat cells. This process has links to obesity as the here is more fat and more inflammation occurs as well as “more glucose is delivered to the fat cells, they produce an excess of reactive oxygen species (ROS) which in turn starts an inflammatory cascade within the cell..”[2] Later when untreated it leads to insulin resistance. Board certified nutritionist Chen Ben Asher suggests to read more about insulin resistance here.

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Ratio balanced macronutrient effect on glucose

The basis to manage blood glucose levels is “40:30:30 dietary approach created in the Joslin Center guidelines.”1 What it means is 40% carbohydrates, 30% protein, 30% fat. The tests done on animals like rat showed that good nutrient ratios also helped to maintain healthy beta cell function. Different other studies have also done on people with the Joslin Diabetes Center in Boston, MA. The recent ones were carried out in 2015 and 2016.

In one of the test results showed glucose control and proportionate response, improvement in HbA1c over 16 weeks of use of balanced medical nutrition therapy and structured meal plan. It also reduces the need for diabetes medications. Together with exercising it also results in a 49% reduction in the risk of developing diabetes. To deal with possible diabesity, it is also important to reduce inflammation. The primary cause of it is the modern lifestyle like consumption of wheat, industrial seed oils, poor sleep, stress, etc.


[1] AANP 2016 Pre-Conference Symposium: Uncontrolled Blood Glucose Effects on Inflammatory Markers. Accessed from:”nofollow”

[2] How inflammation makes you fat and diabetic (and vice versa). Accessed from:”nofollow”

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